REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
17569582
DOI
10.1016/j.sleep.2006.11.018
PII: S1389-9457(06)00713-1
Knihovny.cz E-resources
- MeSH
- Child MeSH
- Humans MeSH
- Narcolepsy complications diagnosis MeSH
- Polysomnography MeSH
- REM Sleep Behavior Disorder complications diagnosis MeSH
- Sleep, REM physiology MeSH
- Severity of Illness Index MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
More than one in three adult patients suffering from narcolepsy-cataplexy experience rapid eye movement (REM) behavior disorder (RBD), while RBD in childhood is extremely rare. We present the cases of two girls (aged 9 and 7 years old) with narcolepsy-cataplexy, in whom RBD was one of the first symptoms of the disease. The coincidence of RBD was seen by nocturnal video-polysomnography (v-PSG), and narcolepsy was diagnosed from short sleep latency and multiple sleep onset REMs (SOREMs) during a multiple sleep latency test (MSLT). Both girls were human leukocyte antigen (HLA)-DQB1 *0602 positive, and their cerebrospinal fluid (CSF) hypocretin level (Hcrt-1) was extremely low.
References provided by Crossref.org
The diagnosis and treatment of pediatric narcolepsy
Narcolepsy: clinical differences and association with other sleep disorders in different age groups
