Aspirin resistance
Jazyk angličtina Země Slovensko Médium print
Typ dokumentu časopisecké články, přehledy
PubMed
17685000
Knihovny.cz E-zdroje
- MeSH
- Aspirin terapeutické užití MeSH
- inhibitory agregace trombocytů terapeutické užití MeSH
- kardiovaskulární nemoci krev prevence a kontrola MeSH
- léková rezistence MeSH
- lidé MeSH
- trombóza prevence a kontrola MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- Aspirin MeSH
- inhibitory agregace trombocytů MeSH
Acetylsalicylic acid, is one of the most effective antiplatelet agents. It effectively reduces the risk of thrombotic events across wide spectrum of patients with cardiovascular disease. However, the treatment failures are relatively common and significant number of patients don't benefit from aspirin therapy. In the last decade the term "aspirin resistance" has been used to describe several different phenomena. This article exposes the difficulties in defining aspirin resistance, discusses the mechanisms by which resistance may occur and deals with its clinical impact. It is necessary to standardize a definition of aspirin resistance, to develop reliable tests for it, and to assess the clinical utility of testing on patients outcomes (Tab. 3, Ref. 60).