Noninvasive detection of vessel stiffness from continuous blood pressure recordings in hypertensive subjects
Language English Country United States Media print
Document type Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
Grant support
HL61560
NHLBI NIH HHS - United States
HL65176
NHLBI NIH HHS - United States
HL70302
NHLBI NIH HHS - United States
HL70602
NHLBI NIH HHS - United States
M01 RR00585
NCRR NIH HHS - United States
- MeSH
- Blood Pressure Monitoring, Ambulatory methods statistics & numerical data MeSH
- Biomedical Engineering MeSH
- Vascular Resistance physiology MeSH
- Adult MeSH
- Photoplethysmography methods statistics & numerical data MeSH
- Hypertension physiopathology MeSH
- Middle Aged MeSH
- Humans MeSH
- Case-Control Studies MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Research Support, N.I.H., Extramural MeSH
This paper presents results of blood pressure dynamicity analysis aimed at vessel stiffness detection and subsequent cardiac risk stratification. We analyzed ECG and BP parameters from 12 normotensive young healthy volunteers, 10 old healthy volunteers, and two groups of hypertensive patients -- 12 young non-medicated hypertensive subjects with no other known complications and 16 hypertensive non-medicated subjects with confirmed obesity (according to waist circumference), hyperlipidemia or diabetes mellitus. The dynamic parameters obtained from a derivative continuous blood pressure signal provide additional information about vessel compliance. They can differentiate hypertensive subjects according to the level of cardiovascular risk.
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