Miniature excitatory synaptic ion currents in the earthworm Lumbricus terrestris body wall muscles
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
17973597
DOI
10.33549/physiolres.931269
PII: 1269
Knihovny.cz E-resources
- MeSH
- Time Factors MeSH
- Cholinergic Antagonists pharmacology MeSH
- Excitatory Postsynaptic Potentials MeSH
- Ion Channels drug effects metabolism MeSH
- Neuromuscular Junction drug effects metabolism MeSH
- Synaptic Transmission * drug effects MeSH
- Oligochaeta metabolism MeSH
- Muscles innervation MeSH
- In Vitro Techniques MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Cholinergic Antagonists MeSH
- Ion Channels MeSH
The miniature excitatory postsynaptic currents (MEPCs) of the muscle cells of the earthworm Lumbricus terrestris were recorded by glass microelectrodes. In a single synaptic zone, three types of MEPC were recorded: a fast single-exponential type that decayed with tau =0.9 ms, a slow single-exponential with tau = 9.2 ms and a two-exponential MEPC with tau = 1.3 and 8.5 ms, respectively. The muscle cells of earthworms contain populations of yet-unidentified ionic channels that might be different from the common nicotinic and muscarinic groups of acetylcholine receptors, since these MEPCs are not sensitive to d-tubocurarine, atropine, benzohexonium or proserine. Alternatively, besides ACh receptors, the membrane may contain receptors for another yet-unidentified excitatory transmitter.
References provided by Crossref.org
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