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Mechanisms of neurogenic pulmonary edema development

. 2008 ; 57 (4) : 499-506. [epub] 20071130

Language English Country Czech Republic Media print-electronic

Document type Journal Article, Research Support, Non-U.S. Gov't, Review

Neurogenic pulmonary edema is a life-threatening complication, known for almost 100 years, but its etiopathogenesis is still not completely understood. This review summarizes current knowledge about the etiology and pathophysiology of neurogenic pulmonary edema. The roles of systemic sympathetic discharge, central nervous system trigger zones, intracranial pressure, inflammation and anesthesia in the etiopathogenesis of neurogenic pulmonary edema are considered in detail. The management of the patient and experimental models of neurogenic pulmonary edema are also discussed.

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