www.rnaworkbench.com: A new program for analyzing RNA interference
Language English Country Ireland Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18207283
DOI
10.1016/j.cmpb.2007.12.001
PII: S0169-2607(07)00300-8
Knihovny.cz E-resources
- MeSH
- Algorithms * MeSH
- Gene Targeting methods MeSH
- RNA, Small Interfering genetics MeSH
- Molecular Sequence Data MeSH
- RNA Interference * MeSH
- Base Sequence MeSH
- Sequence Analysis, RNA methods MeSH
- Sequence Alignment methods MeSH
- Software * MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- RNA, Small Interfering MeSH
RNA interference (RNAi) has become an important tool to study and utilize gene silencing by introducing short interfering RNA (siRNA). In order to predict the most efficient siRNAs, a new software tool, RNA Workbench (RNAWB), has been designed and is freely available (after registration) on http://www.rnaworkbench.com. In addition to the standard selection rules, RNAWB includes the possibility of statistical analyses of the applied selection rules (criteria). The role of RNA secondary structures in the RNA interference process as well as the application of sequence rules are discussed to show the applicability of the software.
References provided by Crossref.org
