www.rnaworkbench.com: A new program for analyzing RNA interference

. 2008 Apr ; 90 (1) : 89-94. [epub] 20080122

Jazyk angličtina Země Irsko Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid18207283
Odkazy

PubMed 18207283
DOI 10.1016/j.cmpb.2007.12.001
PII: S0169-2607(07)00300-8
Knihovny.cz E-zdroje

RNA interference (RNAi) has become an important tool to study and utilize gene silencing by introducing short interfering RNA (siRNA). In order to predict the most efficient siRNAs, a new software tool, RNA Workbench (RNAWB), has been designed and is freely available (after registration) on http://www.rnaworkbench.com. In addition to the standard selection rules, RNAWB includes the possibility of statistical analyses of the applied selection rules (criteria). The role of RNA secondary structures in the RNA interference process as well as the application of sequence rules are discussed to show the applicability of the software.

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