Assessing the antioxidative properties and chemical composition of Linaria vulgaris infusion
Language English Country England, Great Britain Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18569715
DOI
10.1080/14786410601132360
PII: 793969747
Knihovny.cz E-resources
- MeSH
- Biphenyl Compounds chemistry MeSH
- Phenols analysis MeSH
- Hydrazines chemistry MeSH
- Hydroxyl Radical chemistry MeSH
- Hypochlorous Acid chemistry MeSH
- Carboxylic Acids analysis MeSH
- Linaria chemistry MeSH
- Nitric Oxide chemistry MeSH
- Picrates MeSH
- Free Radical Scavengers analysis MeSH
- Superoxides chemistry MeSH
- Chromatography, High Pressure Liquid MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- 1,1-diphenyl-2-picrylhydrazyl MeSH Browser
- Biphenyl Compounds MeSH
- Phenols MeSH
- Hydrazines MeSH
- Hydroxyl Radical MeSH
- Hypochlorous Acid MeSH
- Carboxylic Acids MeSH
- Nitric Oxide MeSH
- Picrates MeSH
- Free Radical Scavengers MeSH
- Superoxides MeSH
The ability of Linaria vulgaris (Scrophulariaceae) infusion to act as a scavenger of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, reactive oxygen species (superoxide radical, hydroxyl radical, hypochlorous acid (HOCl)) and nitric oxide was investigated. The obtained data indicate that the infusion has a good scavenging activity against superoxide radical and is a very potent nitric oxide and DPPH scavenger. In hydroxyl radical assay a pro-oxidant capacity was noticed, especially for concentrations higher than 31.25 microg mL(-1). No effect was found against HOCl. A phytochemical study of this extract was also performed. The HPLC/UV analysis allowed the identification and quantification of eight organic acids (oxalic, aconitic, citric, ketoglutaric, ascorbic, malic, shikimic and fumaric acids). The phenolic composition of the lyophilised infusion was also determined by HPLC/DAD and four compounds were quantified, but, despite its high content, only linarin was managed to be identified.
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