Effects of subchronic metribuzin exposure on common carp (Cyprinus carpio)
Language English Country Sweden Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18987601
PII: NEL290508A02
Knihovny.cz E-resources
- MeSH
- Water Pollutants, Chemical toxicity MeSH
- Cytochrome P-450 CYP1A1 metabolism MeSH
- Herbicides toxicity MeSH
- Liver drug effects metabolism MeSH
- Carps physiology MeSH
- Blood Cell Count MeSH
- Erythrocyte Count MeSH
- Cytochrome P-450 Enzyme System metabolism MeSH
- Triazines toxicity MeSH
- Vitellogenesis drug effects MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Water Pollutants, Chemical MeSH
- Cytochrome P-450 CYP1A1 MeSH
- Herbicides MeSH
- metribuzin MeSH Browser
- Cytochrome P-450 Enzyme System MeSH
- Triazines MeSH
OBJECTIVES: Effects of metribuzin on biochemical and haematological indices, induction of specific biomarkers and impacts on biometric parameters of Cyprinus carpio were investigated for subchronic conditions. METHODS: Juvenile fish were exposed to 0.175 mg.L-1 or 1.75 mg.L-1 metribuzin for 28 days. Haematological indices were assessed using unified methods of haematological examination in fish. Biochemical indices were determined by biochemical analyzer, hepatic vitellogenin content was estimated by direct sandwich ELISA. Cytochrome P450 concentration and ethoxyresorufin O-deethylase activity were measured in liver spectrophotometrically and spectrofluorimetrically, respectively. RESULTS: Increased haematocrit and RBC count were found in fish exposed to 1.75 mg.L-1 metribuzin compared to control fish (p<0.05). Other indices contents and biomarkers levels were not significantly changed by either concentration of metribuzin. CONCLUSION: Sublethal metribuzin pollution may have adverse impacts on haematological parameters in common carp.
The effects of subchronic exposure to metribuzin on Danio rerio
The effects of subchronic exposure to terbuthylazine on early developmental stages of common carp
