Urinary 8-oxodeoxyguanosine levels in children exposed to air pollutants
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
19114049
DOI
10.1016/j.mrfmmm.2008.12.003
PII: S0027-5107(08)00317-5
Knihovny.cz E-resources
- MeSH
- 8-Hydroxy-2'-Deoxyguanosine MeSH
- Deoxyguanosine analogs & derivatives urine MeSH
- Child MeSH
- Air Pollutants urine MeSH
- Humans MeSH
- Particulate Matter urine MeSH
- Child, Preschool MeSH
- Regression Analysis MeSH
- Environmental Exposure * MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Child, Preschool MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- 8-Hydroxy-2'-Deoxyguanosine MeSH
- Deoxyguanosine MeSH
- Air Pollutants MeSH
- Particulate Matter MeSH
Oxidative stress is believed to be one of the mechanisms of effects of air pollution to human health. We investigated levels of 8-oxodeoxyguanosine (8-oxodG), a marker of oxidative damage to DNA, in urine samples of 894 children from two districts in the Czech Republic: Teplice and Prachatice. We assessed the association between 8-oxodG levels and exposure to particulate matter of different size:
References provided by Crossref.org
Biomarkers of nucleic acid oxidation - A summary state-of-the-art