First identification of metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Czech Republic
Language English Country Sweden Media electronic
Document type Case Reports, Journal Article, Research Support, Non-U.S. Gov't
PubMed
19215712
PII: 19102
Knihovny.cz E-resources
- MeSH
- beta-Lactamases metabolism MeSH
- Adult MeSH
- Species Specificity MeSH
- Humans MeSH
- Pseudomonas Infections diagnosis microbiology MeSH
- Pseudomonas aeruginosa classification enzymology isolation & purification MeSH
- Aged MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- beta-lactamase IMP-7 protein, Pseudomonas aeruginosa MeSH Browser
- beta-Lactamases MeSH
Since 2005, invasive isolates of Pseudomonas aeruginosa have been collected in the Czech Republic as part of the European Antibiotic Resistance Surveillance System (EARSS). Forty-eight microbiology laboratories throughout the country including approximately 81% of the population provide consecutive isolates from blood and cerebrospinal fluid. Surprisingly, no metallo-beta-lactamase (MBL) was found in 1,259 invasive isolates tested over the past three years until the detection of two MBL-producing strains in mid-2008. Both strains were isolated from patients hospitalised in one regional hospital. The MBL was identified as IMP-7, which had been seen previously in Canada, Japan, Malaysia and Slovakia.
