Molecular epidemiology of Pseudomonas aeruginosa clinical isolates from Portuguese Central Hospital
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- antibiotická rezistence MeSH
- DNA bakterií analýza MeSH
- genotyp MeSH
- infekce spojené se zdravotní péčí epidemiologie mikrobiologie přenos MeSH
- lidé MeSH
- nemocnice fakultní statistika a číselné údaje MeSH
- polymerázová řetězová reakce MeSH
- pseudomonádové infekce epidemiologie mikrobiologie přenos MeSH
- Pseudomonas aeruginosa genetika izolace a purifikace MeSH
- pulzní gelová elektroforéza MeSH
- vzorkové studie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Portugalsko epidemiologie MeSH
- Názvy látek
- DNA bakterií MeSH
The relatedness between clinical isolates of P. aeruginosa obtained from patients during their stay in a Portuguese Central Hospital was evaluated. Genotypic fingerprinting (M13-PCR), phenotypic methods (biotyping and antibiotyping) and epidemiological information (spatial and temporal links) were used to evaluate the relatedness between 88 clinical isolates (68 patients), selected randomly out of 189. Sixty-two M13 types were found, 12 of them containing isolates from more than one patient. Thirty-four antibiotypes were found, as well as a significant association (p < 0.05) between epidemic isolates and multiresistance patterns. The nosocomial transmission of P. aeruginosa strains may be limited since M13 typing demonstrated a high degree of diversity among all the isolates, suggesting the occurrence of mainly independent infectious episodes. The results show the possible occurrence of cross-acquisition, cross-colonization and cross-infection and suggest an epidemic population structure for P. aeruginosa in this hospital.
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Environ Microbiol. 2005 Jul;7(7):969-80 PubMed
Environ Microbiol. 2002 Dec;4(12):898-911 PubMed
Infection. 1997 Nov-Dec;25(6):350-4 PubMed
J Clin Microbiol. 2007 Apr;45(4):1339-42 PubMed
J Infect Dis. 1993 Oct;168(4):943-7 PubMed
J Bacteriol. 2004 Jul;186(13):4228-37 PubMed
Proc Natl Acad Sci U S A. 2007 May 8;104(19):8101-6 PubMed
J Clin Microbiol. 1994 Mar;32(3):666-71 PubMed
J Clin Microbiol. 1998 Jul;36(7):1846-52 PubMed
Folia Microbiol (Praha). 2006;51(6):633-8 PubMed
J Clin Microbiol. 1999 Nov;37(11):3654-61 PubMed
J Lab Clin Med. 1954 Aug;44(2):301-7 PubMed
Intensive Care Med. 2001 Aug;27(8):1263-8 PubMed
FEMS Immunol Med Microbiol. 2007 Dec;51(3):505-16 PubMed
J Clin Microbiol. 1997 Dec;35(12):3071-7 PubMed
Int J Antimicrob Agents. 2006 Oct;28(4):320-4 PubMed
J Clin Microbiol. 1999 Jun;37(6):1661-9 PubMed
J Clin Microbiol. 1988 Nov;26(11):2465-6 PubMed
J Clin Microbiol. 1995 Sep;33(9):2233-9 PubMed
J Clin Microbiol. 2004 Jun;42(6):2806-9 PubMed
Folia Microbiol (Praha). 2008;53(1):57-60 PubMed
