Response to treatment in women with chronic myeloid leukemia during pregnancy and after delivery

. 2009 Nov ; 33 (11) : 1567-9. [epub] 20090705

Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid19580997
Odkazy

PubMed 19580997
DOI 10.1016/j.leukres.2009.05.012
PII: S0145-2126(09)00262-8
Knihovny.cz E-zdroje

Here we report response to treatment of chronic myeloid leukemia (CML) of five pregnant women during and after pregnancy. CML was diagnosed during pregnancy in three patients. Pregnancy was confirmed during CML in two patients: in one in the 21st week of pregnancy while on imatinib, in another in the 12th week during the interferon treatment. Interferon with leukapheresis when needed was applied in the 2nd and 3rd trimester. All patients except one achieved complete hematological response during pregnancy. After delivery four patients achieved partial cytogenetic response on imatinib and two patients achieved major molecular response after crossover to dasatinib.

Citace poskytuje Crossref.org

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