Eosinophilic meningitis - an immunophenotyping recording of a very rare clinical entity - brief Report
Language English Country United States Media print-electronic
Document type Case Reports, Journal Article
- MeSH
- Eosinophils immunology MeSH
- Glucose cerebrospinal fluid MeSH
- Blood Proteins cerebrospinal fluid MeSH
- Lactic Acid cerebrospinal fluid MeSH
- Humans MeSH
- Meningitis cerebrospinal fluid diagnosis immunology MeSH
- Leukocyte Count MeSH
- Flow Cytometry MeSH
- T-Lymphocytes, Helper-Inducer immunology MeSH
- T-Lymphocytes immunology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Glucose MeSH
- Blood Proteins MeSH
- Lactic Acid MeSH
A very rare clinical entity, so-called eosinophilic meningitis, classified by prevalence of eosinophils in cerebrospinal fluid (CSF), with the presence of pleiocytosis, has been recorded in our laboratory four times only in the last 24 years. A low glucose level, elevation of total protein and lactic acid in CSF were detected in all the clinical cases. The last two cases were made possible by using flow cytometry method; surprisingly, the presence was found in mature T-cells in CSF, predominantly helpers (CD3+, CD4+) and, practically, none is B-cells (CD19+), plasma cells (CD138+) and NK-cells.
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