Anesthesia and the microcirculation
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
19959497
DOI
10.1177/1089253209353134
PII: 1089253209353134
Knihovny.cz E-zdroje
- MeSH
- anestetika inhalační farmakologie MeSH
- anestetika intravenózní farmakologie MeSH
- anestezie metody MeSH
- epidurální anestezie metody MeSH
- kardiopulmonální bypass * MeSH
- lidé MeSH
- mikrocirkulace účinky léků MeSH
- peroperační monitorování metody MeSH
- psi MeSH
- reperfuze MeSH
- tekutinová terapie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- psi MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- anestetika inhalační MeSH
- anestetika intravenózní MeSH
There is increasing evidence that the microcirculation and its regulation are severely compromised during many pathological conditions, such as hemorrhage, sepsis, or trauma. The effects of anesthetic agents on macrohemodynamics were investigated intensively in the last several decades. Research regarding modern anesthetics and anesthesia techniques has increased knowledge regarding the nonanesthetic effects of anesthetic agents, including those on organ perfusion and the microcirculation. Alterations in microvascular reactivity, nitric oxide pathways, and cytokine release are presumably the main mechanisms of anesthetic-induced tissue perfusion changes. This review summarizes current methods of microcirculatory status assessment and current knowledge regarding the microcirculatory effects of intravenous and potent volatile anesthetics and anesthesia-related techniques under both normal and pathophysiological conditions.
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