Unsuccessful therapy of combined mycotic infection in a severely burned patient: a case study
Language English Country Czech Republic Media print
Document type Case Reports, Journal Article
PubMed
20514893
Knihovny.cz E-resources
- MeSH
- Absidia MeSH
- Antifungal Agents administration & dosage therapeutic use MeSH
- Aspergillus fumigatus MeSH
- Aspergillosis drug therapy MeSH
- Adult MeSH
- Fatal Outcome MeSH
- Fusarium MeSH
- Wound Infection drug therapy microbiology MeSH
- Humans MeSH
- Mucormycosis drug therapy MeSH
- Mycoses drug therapy MeSH
- Treatment Failure MeSH
- Burns complications microbiology MeSH
- Pseudomonas Infections drug therapy MeSH
- Pseudomonas aeruginosa MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Antifungal Agents MeSH
Patients with burn trauma are always in danger of contracting an infection. Although invasive mycotic infections are not as frequent as bacterial infections, high mortality and in many cases difficult diagnostics pose a serious threat not only for neutropenic patients. In more extensive burns the status is further complicated by specifically compromised immunity. The most frequent species of micromycetes isolated in burn patients are Candida spp. and Aspergillus spp. Zygomycetes represents a relatively uncommon isolation worldwide (up to 2% of all fungi. We present a case study of a young patient with 82% TBSA (total body surface area) burns, where we isolated simultaneously 3 different types of micromycetes (Aspergillus fumigatus, Fusarium sp., Absidia sp.). Mycotic infection is understood primarily as a complication in neutropenic patients and, after prophylactic antibiotic and antimycotic administration, in extensive burn trauma patients. The case ended with the death of the patient due to severe sepsis caused by the multiresistant strain Pseudomonas aeruginosa.