The paper describes a set of approaches and routines designed to improve results in CT based 3D subtractive angiography of lower extremities via better global locally defined image data registration. Starting from the generic concept of 3D disparity-based flexible registration, modifications of this idea are made founded on prior anatomical knowledge, as segmentation into individual bone areas, their rigid registration followed by constrained flexible registration, and flexible registration of soft tissue volumes. After final subtraction, fusion of the individually derived volumes into the full volume of extremities provides the medically assessable results. The level of detail in minor vessels, and continuity of vessels including those in direct contact with the bones, have been found much better clinically than those achieved by standard contemporary commercial software.

Dept of Biomedical Engineering FEEC Brno University of Technology Czech Republic

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Novel registration-based framework for CT angiography in lower legs