Stochastic model explains the role of excitation and inhibition in binaural sound localization in mammals
Jazyk angličtina Země Česko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
21401305
DOI
10.33549/physiolres.931954
PII: 931954
Knihovny.cz E-zdroje
- MeSH
- akustická stimulace MeSH
- lidé MeSH
- lokalizace zvuku * MeSH
- neurony fyziologie MeSH
- savci MeSH
- sluchová dráha fyziologie MeSH
- stochastické procesy MeSH
- teoretické modely * MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Interaural time differences (ITDs), the differences of arrival time of the sound at the two ears, provide a major cue for low-frequency sound localization in the horizontal plane. The first nucleus involved in the computation of ITDs is the medial superior olive (MSO). We have modeled the neural circuit of the MSO using a stochastic description of spike timing. The inputs to the circuit are stochastic spike trains with a spike timing distribution described by a given probability density function (beta density). The outputs of the circuit reproduce the empirical firing rates found in experiment in response to the varying ITD. The outputs of the computational model are calculated numerically and these numerical simulations are also supported by analytical calculations. We formulate a simple hypothesis concerning how sound localization works in mammals. According to this hypothesis, there is no array of delay lines as in the Jeffress' model, but the inhibitory input is shifted in time as a whole. This is consistent with experimental observations in mammals.
Citace poskytuje Crossref.org
Ergodicity and parameter estimates in auditory neural circuits