Cervical spondylotic myelopathy: conservative versus surgical treatment after 10 years
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, randomizované kontrolované studie, práce podpořená grantem
PubMed
21519928
PubMed Central
PMC3175900
DOI
10.1007/s00586-011-1811-9
Knihovny.cz E-zdroje
- MeSH
- chirurgická dekomprese * MeSH
- činnosti denního života * MeSH
- dospělí MeSH
- komprese míchy chirurgie terapie MeSH
- krční obratle chirurgie MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- posuzování pracovní neschopnosti MeSH
- progrese nemoci MeSH
- prospektivní studie MeSH
- senioři MeSH
- spondylóza chirurgie terapie MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- randomizované kontrolované studie MeSH
It is not known whether the results of decompressive surgery to treat the mild and moderate forms of spondylotic cervical myelopathy (CSM) are any better than those of a conservative approach. A 10-year prospective randomised study was performed. The objective of the study was to compare conservative and operative treatments of mild and moderate, non-progressive, or slowly progressive, forms of CSM. Sixty-four patients were randomised into two groups of 32. Group A was treated conservatively while group B was treated surgically. The clinical outcome was evaluated by modified JOA score, timed 10-m walk, score of daily activities recorded by video and evaluated by two observers blinded to the type of therapy, and by subjective assessment by the patients themselves. Seventeen patents died of natural, unrelated causes, during the follow-up. A total of 25 patients in the conservatively and 22 in the surgically treated group were used for the final evaluation. There was no statistically significant difference between both groups in mJOA score, in subjective evaluation by the patients themselves and in evaluation of video-recordings of daily living activities by two observers blinded to treatment mode. There was neither any difference found in the percentage of patients losing the ability to walk nor in the time taken to cover the 10-m track from a standing start. Comparison of conservative and surgical treatment in mild and moderate forms of CSM in a 10-year follow-up has not shown, on average, a significant difference in results. In both groups, patients get better and worse. According to the power analysis it is necessary admit that these results possess the low ability to answer definitely the question which treatment is better for the patients with a mild and moderate non-progressive CSM because of the low number of patients for the final evaluation and for clinically negligible differences between two compared arms. These findings can serve as a worthy odds-on hypothesis which needs the confirmation.
Zobrazit více v PubMed
Nurick S. The pathogenesis of the spinal cord disorder associated with cervical spondylosis. Brain. 1972;95:87–100. doi: 10.1093/brain/95.1.87. PubMed DOI
Kato Y, Iwasaki M, Fuji T, et al. Long-term follow-up results of laminectomy for cervical myelopathy caused by ossification of the posterior longitudinal ligament. J Neurosurg. 1998;89:217–223. doi: 10.3171/jns.1998.89.2.0217. PubMed DOI
Goto S, Mochizuki M, Watanabe T, et al. Long-term follow-up study of anterior surgery for cervical spondylotic myelopathy with special reference to the magnetic resonance imaging findings in 52 cases. Clin Othop Rel Res. 1993;291:142–153. PubMed
Hirai O, Kondo A, Aoyama I, et al. Anterior decompression surgery of aged patients with cervical myelopathy. No Shinkei Geka. 1991;19:1017–1023. PubMed
Singh A, Choi D, Crockard A. Use of walking data in assessing operative results for cervical spondylotic myelopathy: long-term follow-up and comparison with controls. Spine. 2009;34(12):1296–1300. doi: 10.1097/BRS.0b013e3181a09796. PubMed DOI
Matsumoto M, Chiba K, Ishikawa M, et al. Relationships between outcomes of conservative treatment and magnetic resonance imaging findings in patients with mild cervical myelopathy caused by soft disc herniations. Spine; 2001;26:1592–1598. doi: 10.1097/00007632-200107150-00021. PubMed DOI
Benzel EC, Lancon J, Kesterson L, et al. Cervical laminectomy and dentate ligament section for cervical spondylotic myelopathy. J Spin Disord; 1991;4:286–295. doi: 10.1097/00002517-199109000-00005. PubMed DOI
Dupont WD, Plummer WD (1997) PS power and sample size program available for free on the Internet. Controlled Clin Trials 18:274
Fleiss JL. Statistical methods for rates and proportions. 2. NewYork: John Wiley; 1981. pp. 38–46.
Lehmann EL. Nonparametrics. Statistical methods based on ranks. San Francisco: Holden-Day; 1975.
LaRocca H. Cervical spondylotic myelopathy: natural history. Spine. 1988;13:854–855. doi: 10.1097/00007632-198807000-00028. PubMed DOI
Clarke E, Robinson PK. Cervical myelopathy: a complication of cervical spondylosis. Brain. 1956;79:483–510. doi: 10.1093/brain/79.3.483. PubMed DOI
Epstein JA, Janin Y, Carras R, et al. A comparative study of the treatment of the cervical spondylotic myelopathy. Experience with 50 cases treated by means of extensive laminectomy, foraminotomy, and excision of osteophytes during the past 10 years. Acta Neurochir. 1982;61:89–104. doi: 10.1007/BF01740074. PubMed DOI
Montgomery DM, Brower RS. Cervical spondylotic myelopathy. Clinical syndrome and natural history. Orthop Clin North Am. 1992;23:487–493. PubMed
Sadasivan KK, Reddy RP, Albright JA. The natural history of cervical spondylotic myelopathy. Yale J Biol Med. 1993;66:235–242. PubMed PMC
Symon L, Lavender P. The surgical treatment of cervical spondylotic myelopathy. Neurology. 1967;17(2):117–127. PubMed
Nurick S. The pathogenesis of the spinal cord disorder associated with cervical spondylosis. Brain. 1972;95:87–100. doi: 10.1093/brain/95.1.87. PubMed DOI
Shimomura T, Sumi M, Nishida K, et al. Prognostic factors for deterioration of patients with cervical spondylotic myelopathy after nonsurgical treatment. Spine. 2007;32:2474–2479. doi: 10.1097/BRS.0b013e3181573aee. PubMed DOI
Lees F, Turner JWA. Natural history and prognosis of cervical spondylosis. Br Med J. 1963;2:1607–1610. doi: 10.1136/bmj.2.5373.1607. PubMed DOI PMC
Utley D, Monro P. Neurosurgery for cervical spondylosis. Br J Hosp Med. 1989;42:62–70. PubMed
Rowland LP. Surgical treatment of cervical spondylotic myelopathy. Time for a controlled trial. Neurology. 1992;42:5–13. PubMed
Law MD, Bernhardt M, White AA. Cervical spondylotic myelopathy: a review of surgical indications and decisions making. Yale J Biol Med. 1994;66:165–177. PubMed PMC
Braakman R. Management of cervical spondylotic myelopathy and radiculopathy. J Neurol Neurosurg Psychiatry. 1994;57:257–263. doi: 10.1136/jnnp.57.3.257. PubMed DOI PMC
Ebersold MJ, Pare MC, Quast CM. Surgical treatment for cervical spondylitic myelopathy. J Neurosurg. 1995;82:745–751. doi: 10.3171/jns.1995.82.5.0745. PubMed DOI
Yonebobu K, Hosono N, Iwasaki M, et al. Neurologic complications of surgery for cervical spondylotic myelopathy. Spine. 1991;16:1277–1282. doi: 10.1097/00007632-199111000-00006. PubMed DOI
Gok B, Sciubba DM, McLoughlin GS, et al. Revision surgery for cervical spondylotic myelopathy: surgical results and outcome. Neurosurgery. 2008;63:292–298. doi: 10.1227/01.NEU.0000320441.86936.99. PubMed DOI
Xu BS, Zhang ZL, Le Huec JC, et al. Long-term follow-up results and radiographic findings of anterior surgery with Cloward trephination for cervical spondylotic myelopathy. Spinal Disord Tech. 2009;22:105–113. doi: 10.1097/BSD.0b013e31816d6579. PubMed DOI
Okamoto A, Shinomiya K, Furuya K, et al. Postoperative magnetic resonance in patients with cervical myelopathy. Spine. 1991;39:263–267. PubMed
Kadanka Z, Bednarik J, Vohanka S, et al. Conservative treatment versus surgery in spondylotic cervical myelopathy: a prospective randomised study. Eur Spine. 2000;9:538–544. doi: 10.1007/s005860000132. PubMed DOI PMC
Kadanka Z, Mares M, Bednarik J, et al. Approaches to spondylotic cervical myelopathy: conservative vs surgical results in a three-year follow-up study. Spine. 2002;27:2205–2211. doi: 10.1097/00007632-200210150-00003. PubMed DOI
Kadaňka Z, Mareš M, Bednařík J, et al. Predictive factors for mild forms of spondylotic cervical myelopathy treated conservatively or surgically. Eur J Neurol. 2005;12(1):16–24. doi: 10.1111/j.1468-1331.2004.00947.x. PubMed DOI