Normal sensory and absent cognitive electrophysiological responses in functional visual loss following chemical eye burn
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu kazuistiky, časopisecké články, práce podpořená grantem
- MeSH
- chemické popálení patofyziologie MeSH
- dospělí MeSH
- elektroretinografie MeSH
- kognitivní poruchy patofyziologie MeSH
- lidé MeSH
- popálení oka chemicky indukované MeSH
- poruchy zraku patofyziologie MeSH
- prospektivní studie MeSH
- retina fyziologie MeSH
- senzorické prahy fyziologie MeSH
- testy zrakového pole MeSH
- zraková ostrost fyziologie MeSH
- zraková pole MeSH
- zrakové evokované potenciály fyziologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
OBJECTIVE: To present a unique case of a 34-year-old patient with unilateral functional visual loss after chemical burn with normal visual evoked potentials (VEPs) and absent cognitive response (P300 wave). METHODS: Visual functions, complete ophthalmic and neurologic examinations including computed tomography of the brain, electrophysiological testing of the visual pathway up to the cognitive brain cortex were evaluated. Data were collected prospectively during 1-year follow-up and compared with data from published case series and a literature review. RESULTS: No abnormalities were found that could account for such a rapid monocular loss of vision with exception of absence of the P300 wave in the affected eye during cognitive tasks. Vision slowly improved during 1 year without any treatment. CONCLUSIONS: Functional vision loss is a diagnosis of exclusion. In the event of reduced vision in the context of a normal ocular health examination, all other pathology must be ruled out before the diagnosis of functional visual loss is established. Complex visual electrophysiological testing is the preferred tool for objective examination of such disorders.
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Vision Res. 2007 Jan;47(2):189-202 PubMed
Physiol Res. 2005;54(2):245-50 PubMed
Postgrad Med J. 1999 Apr;75(882):201-7 PubMed
Neuroreport. 1998 Jan 26;9(2):187-91 PubMed
BMJ. 2005 Oct 29;331(7523):989 PubMed
Doc Ophthalmol. 2007 Mar;114(2):83-105 PubMed
Clin Med (Lond). 2002 Nov-Dec;2(6):501-4 PubMed
Doc Ophthalmol. 1992;80(1):83-9 PubMed
Clin Neurophysiol. 2010 Sep;121(9):1464-1472 PubMed
Vision Res. 2006 Feb;46(4):536-44 PubMed
Doc Ophthalmol. 2004 Sep;109(2):169-75 PubMed
Optometry. 2008 Aug;79(8):436-43 PubMed
Vision Res. 2004 Dec;44(26):2989-3000 PubMed
Clin Neurophysiol. 2001 Dec;112(12):2202-8 PubMed
Psychosom Med. 2003 Jul-Aug;65(4):528-33 PubMed
Vision Res. 1995 Jan;35(2):197-205 PubMed
Am J Psychiatry. 2005 May;162(5):847-55 PubMed
J Clin Neurophysiol. 2010 Oct;27(5):334-40 PubMed
Optometry. 2007 Oct;78(10):523-33 PubMed
J Clin Exp Neuropsychol. 1999 Dec;21(6):866-79 PubMed