This study deals with the effect of stimulus contrast, between 1.3% and 96%, on the visual evoked potentials (VEPs) for onset of motion and for pattern reversal of checkerboard stimuli. The VEPs for pattern reversal and for the onset of motion both contain an initial positive peak (P1; peak latency about 120 msec) followed by a later negative peak (N2; peak latency 160-200 msec). However the P1 peak dominates the pattern-reversal VEP when recorded from the midline occipital lead, where it is maximal, while the N2 peak is larger in the motion-onset VEP, especially when recorded from unipolar lateral occipital leads. Whereas the amplitude of the P1 peak in both the pattern-reversal VEP and the motion-onset VEP decreases with decreasing contrast (becoming undetectable at a contrast of about 2% for the motion-onset VEP), the amplitude of the N2 peak in both types of VEP does not vary significantly with contrast, above a contrast of 1.3%. The increase in peak latency with decreasing contrast is also more pronounced for the positive than the negative peaks of both types of VEP. Taking into account the high contrast sensitivity of the magnocellular system (thought to be involved in the processing of motion) compared with the parvocellular system (probably more concerned with the processing of form), our findings suggest that for both motion-onset and pattern-reversal VEPs the negative peak is attributable to the motion-processing magnocellular pathway and the positive peak to the form-processing parvocellular system.

Department of Physiology Medical Faculty of Charles University Hradec Kralové Czech Republic

References provided by Crossref.org

Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research

Difficulties of motion-onset VEP interpretation in school-age children

Normal sensory and absent cognitive electrophysiological responses in functional visual loss following chemical eye burn

An electrophysiological study of visual processing in spinocerebellar ataxia type 2 (SCA2)

Visual evoked potentials to pattern, motion and cognitive stimuli in Alzheimer's disease

Within-session reproducibility of motion-onset VEPs: effect of adaptation/habituation or fatigue on N2 peak amplitude and latency

Motion-onset VEPs to translating, radial, rotating and spiral stimuli

Motion-onset visual evoked potentials improve the diagnosis of glaucoma