Trends in the treatment for liver metastasis of colorectal cancer in Japan
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
22509653
Knihovny.cz E-resources
- MeSH
- Hepatectomy MeSH
- Infusions, Intra-Arterial MeSH
- Colorectal Neoplasms mortality pathology MeSH
- Humans MeSH
- Neoplasm Recurrence, Local MeSH
- Lymph Node Excision MeSH
- Survival Rate MeSH
- Liver Neoplasms mortality secondary therapy MeSH
- Antineoplastic Agents administration & dosage MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Japan epidemiology MeSH
- Names of Substances
- Antineoplastic Agents MeSH
The rate of liver metastasis before surgery of colorectal cancer is 11% in Japan. The survival rate of radical surgery with D-3 lymph node adenectomy is 83.7% in colon cancer and 77.1% in rectal cancer. The percentage of recurrent liver metastasis after curative surgery with D-3 lymph node extent resection is 7.1% within 5 years. Hepatectomy has the best survival rate: 52.8% after 3 years, 39.2% after 5 years. There is no difference in patients' survival rate between systemic anatomical hepatectomy and non-anatomical limited resection. For recurrent hepatic metastasis after curative surgery, hepatectomy should be done if no other metastasis is found in any other organ and the patient is suitable for surgery. Hepatic artery infusion chemotherapy (HAI) for metastasis of the liver is no longer used today. Radiofrequency ablation or microwave coagulation therapy may prolong the survival time but is not a curative procedure.