In vitro antimicrobial activities of cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene against Mycoplasma hominis clinical isolates
Jazyk angličtina Země Česko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
23128812
DOI
10.5507/bp.2012.083
Knihovny.cz E-zdroje
- MeSH
- allylbenzenové deriváty MeSH
- anisoly farmakologie MeSH
- azuleny farmakologie MeSH
- cymeny MeSH
- eugenol farmakologie MeSH
- mikrobiální testy citlivosti MeSH
- monoterpeny farmakologie MeSH
- Mycoplasma hominis účinky léků MeSH
- oleje prchavé farmakologie MeSH
- seskviterpeny guajanové MeSH
- seskviterpeny farmakologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- allylbenzenové deriváty MeSH
- anethole MeSH Prohlížeč
- anisoly MeSH
- azuleny MeSH
- carvacrol MeSH Prohlížeč
- cinnamon oil, bark MeSH Prohlížeč
- cymeny MeSH
- eugenol MeSH
- guaiazulene MeSH Prohlížeč
- monoterpeny MeSH
- oleje prchavé MeSH
- seskviterpeny guajanové MeSH
- seskviterpeny MeSH
AIMS: The aim of this study was to evaluate the antimicrobial effects of five natural substances against 50 clinical isolates of Mycoplasma hominis. METHODS AND RESULTS: The in vitro activity of selected natural compounds, cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene, was investigated against 50 M. hominis isolates cultivated from cervical swabs by the broth dilution method. All showed valuable antimicrobial activity against the tested isolates. Oil from the bark of Cinnamomum zeylanicum (MBC90 = 500 µg/mL) however was found to be the most effective. Carvacrol (MBC90 = 600 µg/mL) and eugenol (MBC90 = 1000 µg/mL) also possessed strong antimycoplasmal activity. CONCLUSIONS: The results indicate that cinnamon bark oil, carvacrol and eugenol have strong antimycoplasmal activity and the potential for use as antimicrobial agents in the treatment of mycoplasmal infections.
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