The variable clinical course of peripartum cardiomyopathy
Language English Country Czech Republic Media print-electronic
Document type Case Reports, Journal Article, Research Support, Non-U.S. Gov't
PubMed
23128823
DOI
10.5507/bp.2012.080
Knihovny.cz E-resources
- MeSH
- Adult MeSH
- Ventricular Dysfunction, Left etiology MeSH
- Dyspnea etiology MeSH
- Fatal Outcome MeSH
- Pregnancy Complications, Cardiovascular diagnosis drug therapy MeSH
- Humans MeSH
- Young Adult MeSH
- Myocarditis complications diagnosis drug therapy MeSH
- Death, Sudden, Cardiac etiology MeSH
- Peripartum Period MeSH
- Heart Failure etiology therapy MeSH
- Pregnancy MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Young Adult MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Research Support, Non-U.S. Gov't MeSH
BACKGROUND: In Europe, peripartum cardiomyopathy (PPCM) is a rare disorder, often difficult to diagnose and it has a variable clinical course. The aim of this report was to describe and discuss the individual variability of this disorder and its management. PATIENTS AND METHODS: Three cases of PPCM manifesting as severe heart failure are compared. Common was the presence of myocardial inflammation detected by endomyocardial biopsy. Different were treatment methods and clinical course. Modern therapeutic concepts such as immunosuppressive therapy and bromocriptin administration are discussed, as well as non-pharmacological approaches. CONCLUSION: In the differential diagnostics of dyspnea associated with pregnancy and childbirth, PPCM should be considered. The potentially severe course of the disease requires hospitalization with the possibility of comprehensive heart failure treatment, including non-pharmacological approaches such as device therapy and heart transplantation.
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