Trace elements in the blood of institutionalized elderly in the Czech Republic
Language English Country Netherlands Media print-electronic
Document type Comparative Study, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
PubMed
23245729
DOI
10.1016/j.archger.2012.11.002
PII: S0167-4943(12)00219-1
Knihovny.cz E-resources
- MeSH
- Middle Aged MeSH
- Humans MeSH
- Manganese blood MeSH
- Copper blood MeSH
- Follow-Up Studies MeSH
- Nutritional Status * MeSH
- Reference Values MeSH
- Retrospective Studies MeSH
- Selenium blood MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Spectrophotometry, Atomic MeSH
- Aging blood MeSH
- Trace Elements blood MeSH
- Zinc blood MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Manganese MeSH
- Copper MeSH
- Selenium MeSH
- Trace Elements MeSH
- Zinc MeSH
Whole blood selenium, copper, zinc and manganese concentrations of 197 institutionalized senior citizens (46 males, 151 females) aged 61-100 years (mean age 83.6 years) were determined using atomic absorption spectrometry and inductively coupled plasma mass spectrometry from two localities in the Czech Republic (Prague and Teplice) from 2009 through 2011. Geometric means (GM) of whole blood selenium (B-Se), copper (B-Cu), zinc (B-Zn) and manganese (B-Mn) levels were 74.0 μg/l, 941.0 μg/l, 5898.0 μg/l and 10.9 μg/l, respectively. Gender-related differences were found with significantly higher B-Cu levels in women and significantly higher B-Zn levels in men. The percentage of seniors with B-Se levels lower than 56 μg/l (which is equivalent to the critical value of 45 μg/l of Se in serum (S-Se)) was 8.6%. A negative correlation between age and B-Se levels was found. B-Zn positively correlated with serum albumin and prealbumin whereas a negative correlation between age and B-Zn was observed. Seniors with diabetes mellitus and atherosclerosis had higher B-Cu and B-Mn levels, respectively, than those without these diagnoses. The elderly from Prague had significantly higher B-Mn concentrations than those from Teplice. We found no evidence of serious essential elements deficiencies or excesses in the seniors who participated in this study.
References provided by Crossref.org
Urinary stones as a novel matrix for human biomonitoring of toxic and essential elements