Completion of cell division is associated with maximum telomerase activity in naturally synchronized cultures of the green alga Desmodesmus quadricauda
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23395610
DOI
10.1016/j.febslet.2013.01.058
PII: S0014-5793(13)00103-8
Knihovny.cz E-resources
- MeSH
- Biological Assay MeSH
- Cell Division MeSH
- Chlorophyta cytology enzymology radiation effects MeSH
- Photoperiod MeSH
- Kinetics MeSH
- Cells, Cultured MeSH
- Plant Proteins isolation & purification metabolism MeSH
- Light MeSH
- Telomerase isolation & purification metabolism MeSH
- Telomere metabolism radiation effects MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Plant Proteins MeSH
- Telomerase MeSH
Telomerase maintains the ends of eukaryotic chromosomes, and its activity is an important parameter correlating with the proliferative capacity of cells. We have investigated cell cycle-specific changes in telomerase activity using cultures of Desmodesmus quadricauda, a model alga naturally synchronized by light/dark entrainment. A quantitative telomerase assay revealed high activity in algal cultures, with slight changes during the light period. Significantly increased telomerase activity was observed at the end of the dark phase, when cell division was complete. In contrast to other models, a natural separation between nuclear and cellular division typical for the cell cycle in D. quadricauda made this observation possible.
References provided by Crossref.org
