Ultrafine particles are not major carriers of carcinogenic PAHs and their genotoxicity in size-segregated aerosols
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23466560
DOI
10.1016/j.mrgentox.2012.12.016
PII: S1383-5718(13)00049-1
Knihovny.cz E-resources
- MeSH
- DNA Adducts MeSH
- Aerosols MeSH
- Carcinogens analysis chemistry MeSH
- Mutagens analysis chemistry MeSH
- Polycyclic Compounds analysis chemistry MeSH
- Particle Size MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- DNA Adducts MeSH
- Aerosols MeSH
- Carcinogens MeSH
- Mutagens MeSH
- Polycyclic Compounds MeSH
Some studies suggest that genotoxic effects of combustion-related aerosols are induced by carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) and their derivatives, which are part of the organic fraction of the particulate matter (PM) in ambient air. The proportion of the organic fraction in PM is known to vary with particle size. The ultrafine fraction is hypothesized to be the most important carrier of c-PAHs, since it possesses the highest specific surface area of PM. To test this hypothesis, the distribution of c-PAHs in organic extracts (EOMs) was compared for four size fractions of ambient-air aerosols: coarse (1
References provided by Crossref.org
TUBE Project: Transport-Derived Ultrafines and the Brain Effects
