Ultrafine particles are not major carriers of carcinogenic PAHs and their genotoxicity in size-segregated aerosols
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
23466560
DOI
10.1016/j.mrgentox.2012.12.016
PII: S1383-5718(13)00049-1
Knihovny.cz E-zdroje
- MeSH
- adukty DNA MeSH
- aerosoly MeSH
- karcinogeny analýza chemie MeSH
- mutageny analýza chemie MeSH
- polycyklické sloučeniny analýza chemie MeSH
- velikost částic MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- adukty DNA MeSH
- aerosoly MeSH
- karcinogeny MeSH
- mutageny MeSH
- polycyklické sloučeniny MeSH
Some studies suggest that genotoxic effects of combustion-related aerosols are induced by carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) and their derivatives, which are part of the organic fraction of the particulate matter (PM) in ambient air. The proportion of the organic fraction in PM is known to vary with particle size. The ultrafine fraction is hypothesized to be the most important carrier of c-PAHs, since it possesses the highest specific surface area of PM. To test this hypothesis, the distribution of c-PAHs in organic extracts (EOMs) was compared for four size fractions of ambient-air aerosols: coarse (1
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TUBE Project: Transport-Derived Ultrafines and the Brain Effects
