The Lesser Egyptian Gerbil (Gerbillus gerbillus) is a suitable host for the long-term propagation of Cryptosporidium andersoni
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23644354
DOI
10.1016/j.exppara.2013.04.007
PII: S0014-4894(13)00128-8
Knihovny.cz E-resources
- Keywords
- Cryptosporidium andersoni, Gerbils, Infection dynamics, Transmission,
- MeSH
- Cryptosporidium growth & development MeSH
- Feces parasitology MeSH
- Gerbillinae parasitology MeSH
- Cryptosporidiosis parasitology veterinary MeSH
- Disease Models, Animal * MeSH
- Mice, Inbred BALB C MeSH
- Mice MeSH
- Cattle Diseases parasitology MeSH
- Stomach Diseases parasitology veterinary MeSH
- Oocysts growth & development MeSH
- Cattle MeSH
- Gastric Mucosa parasitology pathology MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Cattle MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
We describe the course of infection of Cryptosporidium andersoni LI03, originally isolated from cattle, in outbred Gerbillus gerbillus (Lesser Egyptian Gerbil), Meriones unguiculatus (Mongolian gerbil), and Meriones tristrami (Tristram's jird). While both Meriones spp. partially cleared the infection and shed a low number of oocysts (less than 15,000 oocysts per gram (OPG)), chronic infection with a mean infection intensity reaching 200,000 OPG was observed in G. gerbillus. These data suggest that G. gerbillus can be used as a laboratory model for the long-term maintenance and study of C. andersoni without the need for host immunosuppression.
References provided by Crossref.org
Review of Cryptosporidium and Giardia in the eastern part of Europe, 2016