Animals including food animals play a significant role in the epidemiology of Salmonella enterica. The control requires identification of sources and institution of targeted interventions. This study investigates the diversity of S. enterica serovars, antimicrobial susceptibility, and occurrence of plasmid-mediated quinolone resistance (PMQR) genes in pigs in Ibadan, Nigeria. Pooled fresh pen floor fecal samples of pigs collected from 31 pig farms were cultured; the Salmonella isolates were serotyped and their antimicrobial susceptibility was determined. PMQR genes were screened by polymerase chain reaction. The 229 Salmonella isolates were made of 50 serovars predominated by rare serovars Salmonella Give (n = 36; 15.7 %), Salmonella Brancaster (n = 17; 7.4 %), Salmonella Colindale (n = 15; 6.6 %), Salmonella Elisaberthville (n = 13; 5.7 %), Salmonella Hillingdon (n = 13; 5.7 %), and Salmonella Kingston (n = 13; 5.7 %). The most widely distributed serovars among the farms were Salmonella Give (six farms) and Salmonella Elisaberthville (six farms). Resistance to chloramphenicol, sulfonamides, nalidixic acid, streptomycin, and tetracycline ranged from 11.6 % (n = 26) to 22.8 % (n = 51). Resistance ciprofloxacin and gentamicin was low (n = 2; 0.9 %). Multiply resistant isolates included Salmonella Kentucky, the most resistant serovar. qnrB19 was found in two isolates of Salmonella Corvallis and one isolate of Salmonella Larochelle, respectively, while qnrS1 was found in two isolates of Salmonella Derby. Other PMQR genes were not detected. Pigs constitute an important source of diverse Salmonella serovars in Ibadan. The isolates were more resistant to old antimicrobials with some multiple resistant. Control measures and regulation of antimicrobials are warranted.

Department of Microbiology University of Ibadan Ibadan Nigeria

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Euro Surveill. 2008 Jun 12;13(24): PubMed

Geogr Med. 1988;18:171-4 PubMed

Antimicrob Agents Chemother. 2011 Mar;55(3):1148-54 PubMed

J Infect Dev Ctries. 2010 May 01;4(4):243-8 PubMed

Foodborne Pathog Dis. 2005 Fall;2(3):263-73 PubMed

Foodborne Pathog Dis. 2008 Oct;5(5):605-19 PubMed

J Korean Med Sci. 2010 Dec;25(12):1693-9 PubMed

Clin Infect Dis. 2009 Jul 1;49(1):132-41 PubMed

J Appl Microbiol. 2004;96(4):750-60 PubMed

J Infect Dis. 2011 Sep 1;204(5):675-84 PubMed

Int J Food Microbiol. 2007 Sep 15;118(2):116-25 PubMed

J Clin Microbiol. 2000 Dec;38(12):4633-6 PubMed

Obstet Gynecol. 2006 Feb;107(2 Pt 2):516-8 PubMed

J Antimicrob Chemother. 2011 Jun;66(6):1269-72 PubMed

Zentralbl Bakteriol. 1996 Mar;283(3):391-8 PubMed

Vet Res. 2011 Feb 14;42:34 PubMed

Epidemiol Infect. 2012 Oct;140(10):1757-72 PubMed

Curr Opin Infect Dis. 2008 Oct;21(5):531-8 PubMed

Vet Rec. 2009 Nov 28;165(22):648-57 PubMed

Z Gastroenterol. 2005 Aug;43(8):707-13 PubMed

Epidemiol Infect. 2008 Aug;136(8):1118-23 PubMed

Int J Food Microbiol. 2012 Feb 1;153(1-2):45-52 PubMed

Emerg Infect Dis. 2005 Jun;11(6):943-6 PubMed

Antimicrob Agents Chemother. 2009 Feb;53(2):603-8 PubMed

J Antimicrob Chemother. 2009 Feb;63(2):274-81 PubMed

Emerg Infect Dis. 1999 Sep-Oct;5(5):607-25 PubMed

Antimicrob Agents Chemother. 2005 Jul;49(7):3001-3 PubMed

J Infect Dev Ctries. 2010 Sep 03;4(8):484-94 PubMed

Foodborne Pathog Dis. 2004 Winter;1(4):202-15 PubMed

Environ Microbiol. 2004 Aug;6(8):868-71 PubMed

Foodborne Pathog Dis. 2009 Oct;6(8):1009-19 PubMed

Emerg Infect Dis. 2009 Jul;15(7):e2 PubMed