Partial genetic characterization of Sedlec virus (Orthobunyavirus, Bunyaviridae)
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23917024
DOI
10.1016/j.meegid.2013.07.025
PII: S1567-1348(13)00291-8
Knihovny.cz E-resources
- Keywords
- Acrocephalus, Leanyer virus, Orthobunyavirus, Sedlec virus, Simbu group,
- MeSH
- Phylogeny MeSH
- Bunyaviridae Infections virology MeSH
- Virus Cultivation MeSH
- Mice MeSH
- Orthobunyavirus classification genetics isolation & purification MeSH
- RNA, Viral genetics MeSH
- Songbirds virology MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- RNA, Viral MeSH
Sedlec virus (SEDV) was isolated from the blood of a reed warbler (Acrocephalus scirpaceus) in July 1984 in South Moravia, Czech Republic. In this study first genetic data of SEDV are presented which allow an estimate on its phylogenetic and taxonomic positioning within the genus Orthobunyavirus. The phylogenetic analysis of a 369 nt long stretch within the S segment (nucleocapsid protein gene and non-structural S protein gene) indicates genetic relatedness of SEDV to Leanyer virus and Simbu group viruses, while the phylogenetic tree based on 1796nt long sequences of the L segment (RNA-dependent RNA polymerase gene) demonstrates genetic relationship of SEDV to two yet unclassified orthobunyaviruses: I612045 virus (isolated in India in 1961) and Oyo virus (isolated in Nigeria in 1964). Considering the genetic distances and the phylogenetic analyses, SEDV might represent a novel serogroup of the Orthobunyavirus genus.
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