Ochratoxin A levels in blood serum of Czech women in the first trimester of pregnancy and its correspondence with dietary intake of the mycotoxin contaminant
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Validation Study
- MeSH
- Diet * MeSH
- Adult MeSH
- Spectrometry, Fluorescence MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Mycotoxins administration & dosage MeSH
- Ochratoxins blood MeSH
- Pregnancy Trimester, First MeSH
- Pregnancy MeSH
- Chromatography, High Pressure Liquid MeSH
- Environmental Exposure * MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Validation Study MeSH
- Geographicals
- Czechoslovakia MeSH
- Names of Substances
- Mycotoxins MeSH
- ochratoxin A MeSH Browser
- Ochratoxins MeSH
The mycotoxin ochratoxin A (OTA) can elicit a wide range of toxic properties including embryotoxicity and teratogenicity. OTA crosses the placenta at early gestation rather than in late gestation, maternal OTA exposure may represent a risk for the developing fetus. The study focuses on the assessment of OTA intake of pregnant women (aged 19-40 years) in the first trimester of pregnancy by means OTA levels in 100 blood serum samples by high-performance liquid chromotography with fluorescence detection (HPLC-FD) method and comparison with dietary OTA exposure in pregnant women. Of all, 96% tested serum samples were positive with values ranging from 0.1 to 0.35 µg/l with a mean value of 0.15 µg/l.
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