Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in common carp (Cyprinus carpio L.)
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
24238285
DOI
10.1016/j.pestbp.2012.11.002
PII: S0048-3575(12)00174-5
Knihovny.cz E-resources
- MeSH
- Antioxidants metabolism MeSH
- Water Pollutants, Chemical pharmacology MeSH
- Glutathione Reductase metabolism MeSH
- Herbicides pharmacology MeSH
- Carps genetics metabolism MeSH
- Environmental Monitoring MeSH
- Oxidative Stress drug effects MeSH
- Prometryne pharmacology MeSH
- Fish Proteins genetics metabolism MeSH
- Intestines drug effects enzymology MeSH
- Superoxide Dismutase metabolism MeSH
- Muscles drug effects enzymology MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antioxidants MeSH
- Water Pollutants, Chemical MeSH
- Glutathione Reductase MeSH
- Herbicides MeSH
- Prometryne MeSH
- Fish Proteins MeSH
- Superoxide Dismutase MeSH
The effects of the triazine herbicide prometryne, commonly present in surface and ground waters, on oxidative stress and antioxidant status of common carp (Cyprinus carpio) were investigated. Fish were exposed to sublethal concentrations of prometryne (0.51, 8, and 80μg/l) for 14, 30, and 60 days. Activity of superoxide dismutase (SOD), catalase (CAT), and glutathione reductase (GR), as well as levels of thiobarbituric acid reactive substances (TBARSs) were assessed in brain, gill, intestine, liver, and muscle. After 14 days exposure, decreased GR activity in brain was observed for all prometryne-exposed groups compared with the controls. Changes were observed in SOD activity in brain and gill after 30 days in all exposure groups. Changes in CAT activity were observed only at the highest concentration (80μg/l) in liver and intestine after 60 days. The observed effects on carp antioxidant systems may be a defense against oxidative damage. The study demonstrated changes in antioxidant parameters and the importance of evaluating the potential long-term risk to fish of prometryne, at environmentally realistic concentrations (0.51μg/l). The results suggest that antioxidant responses may have potential as biomarkers for monitoring residual triazine herbicides in aquatic environments.
References provided by Crossref.org
Effects of cyhalothrin-based pesticide on early life stages of common carp (Cyprinus carpio L.)
