Preparation, characterization and cytotoxicity of schizophyllan/silver nanoparticle composite
Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
24507278
DOI
10.1016/j.carbpol.2013.11.040
PII: S0144-8617(13)01180-6
Knihovny.cz E-zdroje
- Klíčová slova
- Cytotoxicity, Green synthesis, Schizophyllan, Silver nanoparticles,
- MeSH
- buněčné linie MeSH
- buňky NIH 3T3 MeSH
- difrakce rentgenového záření MeSH
- keratinocyty účinky léků MeSH
- koncentrace vodíkových iontů MeSH
- kovové nanočástice chemie toxicita MeSH
- lidé MeSH
- myši MeSH
- sizofiran chemie toxicita MeSH
- spektrofotometrie ultrafialová MeSH
- spektroskopie infračervená s Fourierovou transformací MeSH
- stříbro chemie MeSH
- teplota MeSH
- transmisní elektronová mikroskopie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- sizofiran MeSH
- stříbro MeSH
Silver nanoparticles (Ag-NPs) have been successfully prepared with a simple and "green" chemical reduction method. Triple helical schizophyllan (SPG) was used for the first time as reducing and stabilizing agents. The effect of temperature, silver nitrate/schizophyllan concentrations, pH of the reactions medium and the reaction time were investigated. The obtained schizophyllan/Ag-NP was characterized by UV-vis spectroscopy, TEM, DLS, X-ray diffraction, TGA, and ATR-FTIR. The results revealed that, Ag-NPs attached to SPG through a strong non-covalent interaction, leading to good dispersion of Ag-NPs with a diameter of 6 nm within the biopolymer matrix. By increasing the pH of the reaction medium, the triple helical structure of SPG was partially broken. The SPG/AgNP nanocomposite was non-toxic for mouse fibroblast line (NIH-3T3) and human keratinocyte cell line (HaCaT).
Central European Institute of Technology Brno University of Technology Brno Czech Republic
Chemistry Department College of Science King Saud University P O 2455 Riyadh 11451 Saudi Arabia
Chemistry Department Faculty of Science Damanhour University Damanhour Egypt
Chemistry Department Faculty of Science Fayoum University Fayoum Egypt
Institute of Materials Chemistry Brno University of Technology Czech Republic
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