Enterocolic lymphocytic phlebitis as a newly recognized manifestation of IgG4-related disease
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu kazuistiky, časopisecké články, práce podpořená grantem
PubMed
24942897
DOI
10.1177/1066896914539549
PII: 1066896914539549
Knihovny.cz E-zdroje
- Klíčová slova
- IgG4, IgG4-related disease, bowel, enterocolic lymphocytic phlebitis,
- MeSH
- enterokolitida imunologie MeSH
- flebitida imunologie MeSH
- imunoglobulin G imunologie MeSH
- lidé MeSH
- nemoci imunitního systému komplikace MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
- Názvy látek
- imunoglobulin G MeSH
Herein we present a case of a 65-year-old woman with enterocolic lymphocytic phlebitis (ELP) who presented with anemic syndrome and in whom severe stenosis of the right flexure of large bowel was detected. The microscopic examination revealed fibrosis of the submucosa and lymphoplasmacytic phlebitis of small veins and venules, whereas arteries were spared. There were 110 IgG4-positive and 160 IgG-positive plasma cells in 1 high-power field, respectively, with corresponding IgG4/IgG ratio of 0.69. The IgG4 serum level was 2.42 g/L. According to the currently proposed criteria, this ELP case is the first that may be diagnosed as definite IgG4-related disease (IgG4-RD). Although based on the sole case description, taken together with a recent review and a case report, we presume that a subset of ELPs is a manifestation of IgG4-RD.
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