Interactions between CdTe quantum dots and DNA revealed by capillary electrophoresis with laser-induced fluorescence detection
Language English Country Germany Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
- Keywords
- Bacteriophage, DNA, Interaction, Quantum dots,
- MeSH
- DNA chemistry metabolism MeSH
- Electrophoresis, Capillary methods MeSH
- Spectrometry, Fluorescence methods MeSH
- Chickens MeSH
- Quantum Dots chemistry metabolism MeSH
- Cadmium Compounds chemistry metabolism MeSH
- Tellurium chemistry metabolism MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- cadmium telluride MeSH Browser
- DNA MeSH
- Cadmium Compounds MeSH
- Tellurium MeSH
Quantum dots (QDs) are one of the most promising nanomaterials, due to their size-dependent characteristics as well as easily controllable size during the synthesis process. They are promising label material and their interaction with biomolecules is of great interest for science. In this study, CdTe QDs were synthesized under optimal conditions for 2 nm size. Characterization and verification of QDs synthesis procedure were done by fluorimetric method and with CE. Afterwards, QDs interaction with chicken genomic DNA and 500 bpDNA fragment was observed employing CE-LIF and gel electrophoresis. Performed interaction relies on possible matching between size of QDs and major groove of the DNA, which is approximately 2.1 nm.
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