Interactions between CdTe quantum dots and DNA revealed by capillary electrophoresis with laser-induced fluorescence detection
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
24981309
DOI
10.1002/elps.201400204
Knihovny.cz E-zdroje
- Klíčová slova
- Bacteriophage, DNA, Interaction, Quantum dots,
- MeSH
- DNA chemie metabolismus MeSH
- elektroforéza kapilární metody MeSH
- fluorescenční spektrometrie metody MeSH
- kur domácí MeSH
- kvantové tečky chemie metabolismus MeSH
- sloučeniny kadmia chemie metabolismus MeSH
- telur chemie metabolismus MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- cadmium telluride MeSH Prohlížeč
- DNA MeSH
- sloučeniny kadmia MeSH
- telur MeSH
Quantum dots (QDs) are one of the most promising nanomaterials, due to their size-dependent characteristics as well as easily controllable size during the synthesis process. They are promising label material and their interaction with biomolecules is of great interest for science. In this study, CdTe QDs were synthesized under optimal conditions for 2 nm size. Characterization and verification of QDs synthesis procedure were done by fluorimetric method and with CE. Afterwards, QDs interaction with chicken genomic DNA and 500 bpDNA fragment was observed employing CE-LIF and gel electrophoresis. Performed interaction relies on possible matching between size of QDs and major groove of the DNA, which is approximately 2.1 nm.
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