Clinical value of assessment of left atrial late gadolinium enhancement in patients undergoing ablation of atrial fibrillation
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
25464485
DOI
10.1016/j.ijcard.2014.11.072
PII: S0167-5273(14)02214-1
Knihovny.cz E-zdroje
- Klíčová slova
- Ablation, Atrial fibrillation, Fibrosis, Magnetic resonance imaging,
- MeSH
- fibrilace síní diagnóza chirurgie MeSH
- gadolinium * MeSH
- katetrizační ablace * metody MeSH
- kontrastní látky MeSH
- lidé středního věku MeSH
- lidé MeSH
- magnetická rezonance kinematografická metody MeSH
- následné studie MeSH
- radionuklidy * MeSH
- senioři MeSH
- srdeční síně patologie chirurgie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- gadolinium * MeSH
- kontrastní látky MeSH
- radionuklidy * MeSH
BACKGROUND: Left atrial (LA) fibrosis begets atrial fibrillation (AF). Cardiovascular magnetic resonance (CMR) using the late gadolinium enhancement (LGE) technique might visualize the LA fibrosis and thus help to choose an appropriate strategy for treatment of AF. In this regard, we investigated whether the extent of preablation LA LGE would predict AF recurrence after ablation in a non-selected patient population. METHODS: CMR was performed in 95 patients before radiofrequency ablation of AF. An interpretable scan was available in 73 patients (age, 59 ± 8 years; men, 71%; persistent/paroxysmal AF, 55/45%). The extent of LA LGE was quantified by three established thresholding techniques. In addition, CMR was used to quantify LA volume and reservoir function. The patients were followed for AF recurrence for 1.3 ± 0.8 years. RESULTS: The arrhythmia recurred in 29 (40%) of the patients. The extent of LA LGE did not differ between paroxysmal and persistent AF and it did not predict the AF recurrence. Moreover, the extent of LA LGE did not correlate with LA volume, reservoir function and bipolar voltage. CONCLUSIONS: Our data indicate a limited value of a routine assessment of LA LGE before ablation of AF. Further experimental and clinical researches should be done before applying the method to a wide clinical practice.
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