A case of cerebral hypoplasia/dysplasia detected at autopsy
Language English Country Czech Republic Media print
Document type Case Reports, Journal Article
PubMed
25671418
PII: 51145
Knihovny.cz E-resources
- MeSH
- Humans MeSH
- Cerebral Cortex abnormalities pathology MeSH
- Death, Sudden etiology pathology MeSH
- Autopsy * MeSH
- Child, Preschool MeSH
- Forensic Pathology * MeSH
- Check Tag
- Humans MeSH
- Child, Preschool MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
UNLABELLED: Presented case was a 2-year-old baby girl who had been treated for nearly one year with the indication of multifocal epileptiform anomaly. She was found dead in her bed in morning hours, autopsy was planned after prosecutors investigation. On internal autopsy examination, shrinkage of gyral structures in the frontal, and parietal lobes of the left hemisphere, markedly enlarged sulci, and a hypoplastic appearance were noted. Histopathological examination revealed evidence of pneumonia, brain exposed microgyral formations, disordered cortical stratification, hypercellularity, dysmorphic neuronal structures, balloon cells with diagnosis of cortical dysplasia. Pneumonia was reported as a cause of death. We aimed to discuss in the light of the literature a case with cerebral hypoplasia which is rarely seen at forensic autopsies. KEYWORDS: cerebral hypoplasia/dysplasia - autopsy - congenital malformation - sudden death.