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Oral penicillin-associated acute kidney injury in an infant with acute pyelonephritis

. 2015 Apr ; 57 (2) : e62-4. [epub] 20150224

Language English Country Australia Media print-electronic

Document type Case Reports, Journal Article, Research Support, Non-U.S. Gov't

Beta-lactam-associated acute tubulointerstitial nephritis (ATIN) is a rare condition in childhood. We report the case of an infant with penicillin-associated ATIN and concomitant acute pyelonephritis resulting in the development of severe acute kidney injury (AKI). The treatment consisted of penicillin suspension and appropriate AKI management, which required a short period of dialysis. Finally, full recovery and normalization of laboratory parameters occurred. We present here the first case of oral penicillin-associated ATIN in childhood.

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