Daily profiles of steroid hormones and their metabolites related to food intake
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26680483
DOI
10.33549/physiolres.933070
PII: 933070
Knihovny.cz E-resources
- MeSH
- Circadian Rhythm physiology MeSH
- Dehydroepiandrosterone blood MeSH
- Adult MeSH
- Estradiol blood MeSH
- Ghrelin blood MeSH
- Sex Hormone-Binding Globulin metabolism MeSH
- Hydrocortisone blood MeSH
- Humans MeSH
- Pregnenolone blood MeSH
- Eating physiology MeSH
- Progesterone blood MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Dehydroepiandrosterone MeSH
- Estradiol MeSH
- Ghrelin MeSH
- Sex Hormone-Binding Globulin MeSH
- Hydrocortisone MeSH
- Pregnenolone MeSH
- Progesterone MeSH
The aim of this study was to look for changes in the daily profile of steroid hormones after standardized food intake. Eight young women not taking contraceptives were followed from 5:30 a.m. till 9:30 p.m. before and 1 and 2 h after eating breakfast, snack, lunch, the second snack and dinner. The differences in steroid levels before and after meals were evaluated. As expected, glucose, C-peptide and ghrelin levels changed postprandially. The steroid hormones cortisol, progesterone, pregnenolone and dehydroepiandrosterone showed a decrease after main meals, whereas testosterone and dihydrotestosterone showed no significant dependence on food intake. Estrogen levels did not exhibit a significant nycthemeral rhythm, but estradiol decreased after main meals. In our study the known nycthemeral rhythm of LH, FSH, cortisol, progesterone and pregnenolone after food intake were confirmed, but significant changes after meals were also observed in the levels of cortisol, dehydroepiandrosterone, estradiol and SHBG.
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