Sleep, sleep deprivation, autonomic nervous system and cardiovascular diseases
Language English Country United States Media print-electronic
Document type Journal Article, Review
PubMed
27397854
DOI
10.1016/j.neubiorev.2016.07.004
PII: S0149-7634(16)30218-4
Knihovny.cz E-resources
- Keywords
- Apnea *, Autonomic nervous system *, Cardiovascular diseases *, Sleep deprivation *,
- MeSH
- Autonomic Nervous System * MeSH
- Cardiovascular Diseases * MeSH
- Humans MeSH
- Sleep Apnea, Obstructive MeSH
- Risk Factors MeSH
- Sleep Deprivation * MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Sleep deprivation (SD) has become a relevant health problem in modern societies. We can be sleep deprived due to lifestyle habits or due to sleep disorders, such as insomnia, obstructive sleep apnea (OSA) and neurological disorders. One of the common element of sleep disorders is the condition of chronic SD, which has complex biological consequences. SD is capable of inducing different biological effects, such as neural autonomic control changes, increased oxidative stress, altered inflammatory and coagulatory responses and accelerated atherosclerosis. All these mechanisms links SD and cardiovascular and metabolic disorders. Epidemiological studies have shown that short sleep duration is associated with increased incidence of cardiovascular diseases, such as coronary artery disease, hypertension, arrhythmias, diabetes and obesity, after adjustment for socioeconomic and demographic risk factors and comorbidities. Thus, an early assessment of a condition of SD and its treatment is clinically relevant to prevent the harmful consequences of a very common condition in adult population.
C Munari Center of Epilepsy Surgery Niguarda Hospital Milan Italy
Department of Internal Medicine L Sacco Hospital Milan Italy
Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico Milan Italy
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