Carbohydrate-modified magnetic nanoparticles for radical scavenging
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
27762590
DOI
10.33549/physiolres.933426
PII: 933426
Knihovny.cz E-resources
- MeSH
- Dioxolanes chemistry MeSH
- Furans chemistry MeSH
- Glucose chemistry MeSH
- Ascorbic Acid chemistry MeSH
- Magnetite Nanoparticles chemistry ultrastructure MeSH
- Silicon Dioxide chemistry MeSH
- Free Radical Scavengers chemical synthesis MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- 5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro(2,3-d)(1,3)dioxol-6-yl(3-(tritriethoxysilyl) MeSH Browser
- Dioxolanes MeSH
- Furans MeSH
- Glucose MeSH
- Ascorbic Acid MeSH
- Magnetite Nanoparticles MeSH
- Silicon Dioxide MeSH
- Free Radical Scavengers MeSH
Maghemite (gamma-Fe2O3) nanoparticles, 12 nm in size, were prepared by co-precipitation of Fe(II) and Fe(III) chlorides with ammonium hydroxide and oxidation with hydrogen peroxide. To achieve stability and biocompatibility, obtained particles were coated with silica, to which glucose and ascorbic acid were bound by different mechanisms. The composite particles were thoroughly characterized by transmission electron microscopy, dynamic light scattering, elemental analysis, and FT-Raman and fluorescence spectroscopy to determine composition, morphology, size and its distribution, zeta-potential, and scavenging of peroxyl and hydroxyl radicals. As the particles showed promising antioxidative properties, they may have a possible application as a stable magnetically controlled scavenger of reactive oxygen species.
References provided by Crossref.org
The negative effect of magnetic nanoparticles with ascorbic acid on peritoneal macrophages
