Influence of Prescribed Blood Products on the Incidence of Deep Vein Thrombosis and Pulmonary Embolism in Surgical Patients
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu klinické zkoušky, časopisecké články
PubMed
28118751
DOI
10.1177/1076029616689301
Knihovny.cz E-zdroje
- Klíčová slova
- blood replacement, prevention of venous thromboembolism, red blood cells, vitamin K,
- MeSH
- heparin nízkomolekulární aplikace a dávkování MeSH
- incidence MeSH
- krevní plazma * MeSH
- lidé středního věku MeSH
- lidé MeSH
- plicní embolie epidemiologie etiologie terapie MeSH
- pooperační komplikace epidemiologie terapie MeSH
- retrospektivní studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- transfuze erytrocytů * MeSH
- vitamin K aplikace a dávkování MeSH
- žilní trombóza epidemiologie etiologie terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky MeSH
- Názvy látek
- heparin nízkomolekulární MeSH
- vitamin K MeSH
Deep vein thrombosis (DVT) and pulmonary embolisms (PEs) are common complications after surgical procedures. The influence of prescribed blood products on the occurrence of DVT and PE was evaluated in postsurgical patients in this retrospective case-control study. The records of 286 surgical patients were analyzed: DVT (n = 52), PE (n = 92), and a control group (n = 142). The amounts of prescribed blood, blood products, and vitamin K were reviewed, together with appropriate prescribing of low-molecular-weight heparins. The influence of prescribed blood products on the occurrence of DVT or PE was analyzed using multinomial logistic regression. We demonstrated a significant difference between the test and control groups ( P < .05) in relation to receiving packed red blood cells. Treatment with red blood cells was associated with an increased risk of PE but not DVT. Patients who developed PE after surgery were hospitalized for longer (median 10 days) than patients with DVT (median 6 days). There was no difference between the test and control groups concerning treatment with fresh frozen plasma. Inadequate thromboprophylaxis significantly increased the likelihood of DVT. There is a connection between receiving packed red blood cells and occurrence of postoperative PE in surgical patients. Thus, patients receiving red blood cells should be monitored more closely after surgery, as they are more likely to develop PE postoperatively.
2nd Department of Internal Medicine Comenius University and University Hospital Bratislava Slovakia
2nd Department of Surgery Masaryk University Brno Czech Republic
Department of Thoracic Surgery Medical University of Silesia Katowice Poland
Faculty of Medicine Institute of Histology and Embryology University of Ljubljana Ljubljana Slovenia
Faculty of Pharmacy University of Ljubljana Ljubljana Slovenia
Hospital Pharmacy General Hospital Murska Sobota Murska Sobota Slovenia
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