Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
29017785
DOI
10.1016/j.bmcl.2017.09.064
PII: S0960-894X(17)30973-3
Knihovny.cz E-resources
- Keywords
- Carboranes, DNA polymerase, Nucleoside triphosphates, Nucleotides, Oligonucleotides,
- MeSH
- Boranes chemistry MeSH
- Deoxyuracil Nucleotides chemistry MeSH
- DNA Primers chemistry metabolism MeSH
- DNA-Directed DNA Polymerase metabolism MeSH
- DNA biosynthesis chemistry MeSH
- Oligonucleotides biosynthesis chemistry MeSH
- Polymerase Chain Reaction MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Boranes MeSH
- Deoxyuracil Nucleotides MeSH
- deoxyuridine triphosphate MeSH Browser
- DNA Primers MeSH
- DNA-Directed DNA Polymerase MeSH
- DNA MeSH
- Oligonucleotides MeSH
5-[(p-Carborane-2-yl)ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases.
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