Enantioselective complexation of 1-phenylethanol with chiral compounds bearing urea moiety
Status PubMed-not-MEDLINE Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
29578615
DOI
10.1002/chir.22855
Knihovny.cz E-zdroje
- Klíčová slova
- [6]helicene, binaphthalene, calix[4]arene, enantioselective complexation, urea,
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
A detailed study of diastereomeric complexes of chiral ureido-1,1'-binaphthalene derivatives with chiral 1-phenylethanol showed that a derivative bearing only one urea unit makes five times more stable complex with (S)-enantiomer than with (R)-enantiomer of the alcohol. This phenomenon could be used in chiral discrimination processes. The influence of individual parts of the structure on the complexation properties is shown. The probable structure of diastereomeric complexes based on experimental results and computational methods is proposed.
Department of Organic Chemistry University of Chemistry and Technology Prague Czech Republic
Institute of Chemical Process Fundamentals of the Czech Academy of Sciences Prague Czech Republic
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