Exogenous surfactant as a bridge to prolonged "total lung rest" in severely injured patient during extracorporeal membrane oxygenation
Language English Country Japan Media print-electronic
Document type Case Reports, Journal Article
Grant support
MH CZ - DRO - FNOs/2013
MH CZ - DRO - FNOs/2013
PubMed
29582175
DOI
10.1007/s10047-018-1037-2
PII: 10.1007/s10047-018-1037-2
Knihovny.cz E-resources
- Keywords
- Acute respiratory distress syndrome, Exogenous surfactant, Extracorporeal membrane oxygenation, Total lung rest,
- MeSH
- Hypoxia diagnostic imaging physiopathology therapy MeSH
- Humans MeSH
- Extracorporeal Membrane Oxygenation methods MeSH
- Young Adult MeSH
- Lung diagnostic imaging physiopathology MeSH
- Tomography, X-Ray Computed MeSH
- Surface-Active Agents therapeutic use MeSH
- Respiratory Distress Syndrome diagnostic imaging physiopathology therapy MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Surface-Active Agents MeSH
We report a case of a 20-year-old male patient suffering from motorcycle accident complicated by rapid development of severe refractory hypoxemia and hypercapnia due to serious bilateral lung contusions and lacerations. Positive pressure mechanical ventilation induced pressure-dependent massive air leak from disrupted pulmonary tissue. Simultaneous implementation of veno-venous extracorporeal membrane oxygenation together with surfactant application allowed prolonged disconnection of patient from mechanical ventilation ("total lung rest" mode). Despite considerable areas of nonaerated tissue on computed tomography prior to the disconnection from mechanical ventilation, almost total functional recovery of lungs was eventually achieved.
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