Respiratory microsporidiosis caused by Enterocytozoon bieneusi in an HIV-negative hematopoietic stem cell transplant recipient
Jazyk angličtina Země Kanada Médium print-electronic
Typ dokumentu kazuistiky, časopisecké články
PubMed
30063985
DOI
10.1016/j.ijid.2018.07.021
PII: S1201-9712(18)34482-5
Knihovny.cz E-zdroje
- Klíčová slova
- Enterocytozoon bieneusi, Hematopoietic stem cell transplant, Respiratory tract infection,
- MeSH
- albendazol terapeutické užití MeSH
- bronchoalveolární laváž MeSH
- Enterocytozoon účinky léků izolace a purifikace MeSH
- HIV infekce MeSH
- imunokompromitovaný pacient účinky léků MeSH
- infekce močového ústrojí diagnóza farmakoterapie MeSH
- levofloxacin terapeutické užití MeSH
- lidé MeSH
- mikrosporidióza diagnóza farmakoterapie MeSH
- mladý dospělý MeSH
- rizikové faktory MeSH
- transplantace hematopoetických kmenových buněk * MeSH
- Check Tag
- lidé MeSH
- mladý dospělý MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- albendazol MeSH
- levofloxacin MeSH
A 23-year-old, HIV-negative woman who had undergone a hematopoietic stem cell transplantation was admitted to the hospital with respiratory failure and symptoms of bronchiolitis obliterans. A chest computed tomography scan revealed diffuse ground-glass opacification and fibrous plugs. Due to worsening respiratory failure despite treatment, ventilation was provided through a tracheostomy tube. Molecular examination of bronchoalveolar lavage and urine revealed Enterocytozoon bieneusi infection. After treatment with albendazole the patient gradually improved, but the pathogen was not eradicated and reappeared on follow-up examination. E. bieneusi belongs to the most clinically important microsporidial species infecting humans, mostly those who are immunocompromised. This fungus tends to infect enterocytes of the intestine, and there are limited studies concerning its extraintestinal location. This is the first report of a case of disseminated respiratory and urinary E. bieneusi infection in a transplant recipient.
Department of Biology and Medical Parasitology Wroclaw Medical University Wroclaw Poland
Lower Silesian Center for Cellular Transplantations Wroclaw Poland
Citace poskytuje Crossref.org
Chronic Infections in Mammals Due to Microsporidia
