Abdominal wall allotransplantation
Language English Country Czech Republic Media print-electronic
Document type Journal Article, Review
PubMed
30209436
DOI
10.5507/bp.2018.038
Knihovny.cz E-resources
- Keywords
- abdominal wall transplantation, vascularized composite allotransplantation,
- MeSH
- Abdominal Wall surgery MeSH
- Immunosuppressive Agents therapeutic use MeSH
- Practice Patterns, Physicians' MeSH
- Humans MeSH
- Cadaver MeSH
- Graft Rejection etiology MeSH
- Skin Transplantation methods MeSH
- Vascularized Composite Allotransplantation methods MeSH
- Donor Selection methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Immunosuppressive Agents MeSH
Allotransplantation of vascularized composite tissue is a new field of transplantation surgery. One application of this technique is abdominal wall transplantation used as a supplementary procedure to the transplantation of visceral organs in patients with abdominal compartment deficits. As abdominal wall closure problems are experienced in around 30-40% of such patients, peer reviewed conclusions on the viability of various options, are important for an informed choice of possible procedures. This review focuses on the abdominal wall allotransplantion procedure. Our search provided 35 appropriate references which we used to support our findings as follows: abdominal wall transplantation was performed in 33 patients at seven centres. Of these, 30 had a full thickness abdominal wall transplanted from the same donor, 3 from a second donor. Three had visceral organ transplants and in addition, the posterior sheet of the rectus muscle fascia. In summary, our findings were that abdominal wall allotransplantation does not jeopardize the outcome of visceral organs transplantation. There is no higher risk of complications or rejection of the visceral organs. There have been no fatalities as a direct result of complications due to abdominal wall transplantation. Finally, the transplanted abdominal wall may provide an early warning of rejection before diagnostic tests on the bowel are symptomatic.
References provided by Crossref.org