Hydrogen sulfide plays an important protective role by influencing autophagy in diseases
Language English Country Czech Republic Media print-electronic
Document type Journal Article, Review
PubMed
30904008
DOI
10.33549/physiolres.933996
PII: 933996
Knihovny.cz E-resources
- MeSH
- Autophagy physiology MeSH
- Cytoprotection drug effects physiology MeSH
- Gasotransmitters metabolism MeSH
- Ischemia drug therapy metabolism MeSH
- Humans MeSH
- Cell Proliferation drug effects physiology MeSH
- Hydrogen Sulfide administration & dosage metabolism MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Gasotransmitters MeSH
- Hydrogen Sulfide MeSH
Autophagy can regulate cell growth, proliferation, and stability of cell environment. Its dysfunction can be involved in a variety of diseases. Hydrogen sulfide (H(2)S) is an important signaling molecule that regulates many physiological and pathological processes. Recent studies indicate that H(2)S plays an important protective role in many diseases through influencing autophagy, but its mechanism is not fully understood. This article reviewed the progress about the effect of H(2)S on autophagy in diseases in recent years in order to provide theoretical basis for the further research on the interaction of H(2)S and autophagy and the mechanisms involved.
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